Weak/Substantial Metabolizers, CYP2D6 The formation with the Energetic metabolite, M1, is mediated by CYP2D6, a polymorphic enzyme. Roughly seven% in the populace has lessened action on the CYP2D6 isoenzyme of cytochrome P450 metabolizing enzyme procedure. These people are “inadequate metabolizers” of debrisoquine, dextromethorphan and tricyclic antidepressants, amongst other medicati... https://roberti531lrv6.blogthisbiz.com/profile