Topical Treatment plans Above-The-Counter Medicine About-the-counter creams and ointments, Specifically people who consist of capsaicin, an extract derived from chili peppers, may be applied topically for the knee that can help relieve pain by decreasing the depth of pain indicators sent alongside nerve pathways. Corticosteroid injections can help minimize inflammation https://www.theorthopaedicandpainpractice.com/understanding-and-treating-elderly-knee-pain/